York Festival of Ideas: Regenerative Medicine and Time to the Clinic

Sociology has always had a strong interest in medicine, and more recently, in the impact of the new biomedical sciences on medicine. The social science grant agency, the ESRC is itself keen to support new work on ‘the biosocial’, how the social and the biological are co-produced. One area where the biosocial is especially important for sociological inquiry is Regenerative Medicine (RM). Its distinctive feature is the use of live cells and tissues to treat disease, replacing diseased tissue and organs with new, healthy and specially-grown tissue. Within the UK, the field of RM is surrounded by considerable promise and high expectation. It is championed as a potential source of cures for a range of disorders, and the Government has identified the field as one of the wealth-generating  ‘Eight Great Technologies’ which help drive the economic growth.  In light of this, various Government-supported initiatives have been launched to accelerate innovation within the field and bring new therapies to patients sooner.

The field of RM, however, is still very much in its infancy, and there are very few therapies available in the present day. Sociological research being undertaken by members of SATSU in the Department shows how clinicians and investigators working on new RM therapies are encountering many significant challenges that reflect the ‘biosocial’ at work: how to stabilise and standardise the tissue they work with, what sort of legal and regulatory classification it should have compared to other areas of medicine, whether they need new types of organisational and clinical systems to deliver RM to patients, and how should the long term benefits and costs of RM be assessed?

As part of the York Festival of Ideas, Andrew Webster, Ruchi Higham and John Gardner from the Sociology Department will join Paul Genever and Amanda Barnes from the Department of Biology will lead a public discussion on RM. By bringing the biological and social sciences together, they will provide an overview of the hopes (and hype) but, more importantly, the likely and diverse clinical paths that regenerative medicine will take and within what timeframes. The session will involve a lively and informed debate about RM and help participants to understand better its likely long-term impact in the NHS and elsewhere.

Details:

June 9^th, 6:00pm – 7:30pm

The Diana Bowles Lecture Theatre, Department of Biology. Room K018 (Ground floor Biology Building)

Admittance/ticket price: Free entry

Booking details Via the Central Festival Team

Website: www.york.ac.uk/satsu/regenablemed

Regenerative Medicine and Sociology

Sociology has always had a strong interest in medicine, and more recently, in the impact of the new biomedical sciences on medicine. An emerging area for sociological inquiry is Regenerative Medicine (RM) which Andrew Webster has already published on. Its distinctive feature is the use of live cells and tissues to treat disease, replacing diseased tissue and organs with new, healthy and specially-grown tissue. There has been considerable social and political controversy surrounding the use of cells, especially embryonic stem cells, but these debates have largely subsided, and now RM is widely heralded as potential source of cures for a range of illnesses.

The field of RM, however, is still very much in its infancy, and there are very few therapies available in the present day. Clinicians and investigators working on new RM therapies are encountering many significant challenges relating to financing, manufacturing, regulation, and organisational inertia. These pose important questions that sociology can address, especially in terms of how healthcare systems such as the NHS may – or indeed, may not – embrace and embed biomedical innovation. 

Equally importantly, RM raises questions about ‘Life’, in the form of tissues and cells, and how this is being manipulated, harnessed and in some cases commercialised in the name of ‘health and wealth’. Simultaneously, new social groups and agencies are forming to govern and facilitate this harnessing of life. From a sociological standpoint, we may ask: how do these novel forms of life reflect their cultural context? How do they change the boundaries of what is seen as ‘life’ itself? What discourses are being mobilised to promote innovation? What novel social organisations are emerging, and how do these upset or reaffirm traditional professional divisions?  Whose viewpoints and interests are being heard, and whose are being ignored? And more broadly: how exactly are social concerns and technological developments intertwined and shaping one another?

John Gardner

Andrew Webster

It is these types of questions that are being addressed by our ESRC-fundedREGenableMED project.  The project team comprises ten researchers from the Universities of York (Andrew Webster, Graham Lewis and John Gardner), Edinburgh, Birmingham and Sussex, with specific expertise in science and technologies studies, law, commercialisaiton, and technology horizon scanning.  The three year project is now into its second year, and we have been interviewing a range of stakeholders in the RM field, as well as collecting reams of secondary data on clinical and commercial activity, much of which is being collated in an extensive database. Our first paper, which explores the perceived novelty of RM will soon be published in RegenerativeMedicine in September. Ultimately, we hope that our broad, sociological perspective on the field will enable us to inform and guide responsible innovation in the area.    

Postdoctoral Research Associate, Science and Technology Studies Unit

A 3 year full-time post-doc position is available in SATSU to work on a new ESRC-funded project on regenerative medicine. Click on the University Jobs page for more details.

The position will involve working closely with the Director of the Unit on a newly funded ESRC research project in the sociology of the biosciences, focusing on the field of regenerative medicine and stem cell therapies: ‘Regenerative medicine and its development and implementation: an analysis of emergent value systems and health’.